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Symbol
Name
ID

Havcr2
hepatitis A virus cellular receptor 2
MGI:2159682

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Subacute progressive viral hepatitis
Disease(s) Associated with HAVCR2	Subacute progressive viral hepatitis
hepatocellular carcinoma

Mouse Phenotypes		immune system phenotype	decreased activation-induced cell death of T cells	decreased T cell proliferation	increased spleen weight	decreased T cell number	abnormal CD8-positive, alpha-beta T cell physiology	decreased interferon-gamma secretion	decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	decreased susceptibility to Orthomyxoviridae infection
Availability	Mouse Genotype	immune system phenotype	decreased activation-induced cell death of T cells	decreased T cell proliferation	increased spleen weight	decreased T cell number	abnormal CD8-positive, alpha-beta T cell physiology	decreased interferon-gamma secretion		decreased susceptibility to Orthomyxoviridae infection
	Havcr2^{tm1b(KOMP)Wtsi}/Havcr2^{tm1b(KOMP)Wtsi}
	Havcr2^tm1Bmed/Havcr2^tm1Bmed
	Havcr2^tm1Tbs/Havcr2^tm1Tbs	*
	Havcr2^tm1Vlcg/Havcr2^tm1Vlcg

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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